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Therapy of chronic wasting


The enormous weight loss that is associated with HIV in advanced stages continues to represent an important psychological and physical problem, that limits social interactions and reduces life quality of affected individuals.


A trial with "oxymetholone", a derivative of testosterone, demonstrated the accrual of body cell mass in wasted patients. Following this success, the effects of this anabolic drug are currently being studied with respect to body composition (muscle, fat and water) in 100 patients.


The goal remains to fight wasting and body fat redistribution (e.g. crix-belly, buffalo-hump, and slim-cheeks).


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